Polyamines

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منابع مشابه

Polyamines and prostatic cancer.

The importance of polyamines in prostatic growth and differentiation has prompted studies to evaluate the clinical relevance of the ornithine decarboxylase/polyamine system in prostatic cancer. These studies show that differences in biological behaviour of prostatic (cancer) cells are associated with changes in polyamine levels and/or the activity of their metabolic enzymes. Faulty antizyme reg...

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Polyamines and plant alkaloids.

Naturally occurring alkaloids are nitrogenous compounds that constitute the pharmacogenically active basic principles of flowering plants. Alkaloids are classified into several biogenically related groups. Tobacco alkaloids are metabolised from polyamines and diamines putrescine and cadaverine. N-methyl transferase is the first enzyme in alkaloid biosynthetic pathway which drives the flow of ni...

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Polyamines in inflammation

esults on page 257 by Soulet and Rivest implicate polyamines in controlling immune responses in the brain. Their results suggest that polyamine synthesis, if left unchecked, can cause damaging inflammatory responses reminiscent of neurodegenerative disorders. Recognition of bacterial and viral pathogens by microglial cells, the brain’s equivalent of macrophages, elicits a cascade of gene expres...

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Polyamines and colon cancer.

In colon cancer, the activities of polyamine-synthesizing enzymes and polyamine content are increased 3-4-fold over that found in the equivalent normal colonic mucosa, and polyamines have even been attributed as markers of neoplastic proliferation in the colon. Furthermore, and in contrast with all other cell systems in the body, normal and neoplastic cells in the colon are exposed to high conc...

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Polyamines in intestinal growth.

The total cellular mass of the small intestine is well controlled and can adapt, with hypo- or hyperplasia, to a wide variety of stimuli. Luminal nutrients, hormonal factors and pancreatic and biliary secretions have all been implicated in the regulation of intestinal mucosal growth. The polyamines (putrescine, spermidine and spermine) and the key enzyme controlling their synthesis (ornithine d...

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ژورنال

عنوان ژورنال: NIPPON SHOKUHIN KAGAKU KOGAKU KAISHI

سال: 2014

ISSN: 1341-027X,1881-6681

DOI: 10.3136/nskkk.61.607